The natural habitat of Nematostella is marsh lands, hence they constantly adapt to changes in salinity, temperature, oxygen concentration and pH. Due to its ability to adapt to a changing environment, its genetic tractability and its ability to survive without their microbiome we have selected Nematostella as a model system to investigate the effect of pollutants on tissue regeneration and the microbiome. The project is in collaboration with the labs of A. Murat Eren at the University of Chicago and Karen Echeverri at MBL. We received pilot funding from the Microbiome Center as well as support from the McDonnell Initiative.